Juju,
My layout is somewhat like Eric has. The main texture folder has 374 folders & sub folders which contains 36,442 files and my component folder has 1,084 folders & sub folders which contains 38,005 files. I know a bit extreme but this is a collection of about 11 years. The funny thing about this is that I know where everything is.
http://www.sketchucation.com/forums/scf/sas/Components/components.jpg
http://www.sketchucation.com/forums/scf/sas/Components/textures.jpg