Thanks for posting this ... this morning my Win 7 64 machine (Lenovo T400 with ATI graphics) refused load SU 8 without Bugsplatting within seconds. I have win Update set to manual and may have updated something like a Defender file late last night, but nothing major.
GOOD NEWS - removing LIBFREDO6_Dir_47 has stopped the crashing. I had already tried removing TT stuff (started there because of the .dll objections posed by Online Armour, not because of any doubts about TT, or Fredo, both of whom I hold in awe for their excellent plugins) and was working my way through when I saw this post.
So ... Thank you, again
<edit> SU 8.0.16846
Checked update logs ... updated Defender definition KB915597 2days ago (22 Mar) but didn't restart from off until this morning, Next most recent Cumulative security updates KB2809289 and KB2807986 (as mentioned by OP) plus a number of others (Silverlight, MSRT, defimition updates etc.) on 14-Mar but I have restarted numerous times since & using SU each session.
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