I recently switched to Vista, (nearly switched to a Mac - might have been better). I have discovered that
Architectural desktop 2006
3DS Max 6 - 8
Pov-Ray
V-Ray
Truespace
PowerCAD
Revit (before latest release, only tried an older version)
TurboCAD (ditto)
AutoCad versions previous to 2008
Sketchy Physics and several other Su plugins
Loads of useful older software that i have
won't run or don't run properly on Vista. Maybe there are ways to get them to run but I don't have the time or the inclination to find out and at the moment can't afford the software upgrades. ProgeCAD and Cycas run fine on Vista so I can still do CAD.
In general though, as an OS for design software, Vista sucks in my opinion, but it does look nice and er, that's it. No other real advantages that I can see.
I heard Dell have dropped Vista completely for Ubuntu Linux. And SU will run on linux. See link.
http://uk.youtube.com/watch?v=gKcepdfm5C8&feature=RecentlyWatched&page=1&t=t&f=b