First thing, don't give up!
I have become an old hand at keeping old machines alive.
If you can't reinstall, you need to do a major cleanup. Be prepared to spend some time.
Get rid of Windows Bloat:
http://articles.networktechs.com/printer-69.html
Get good antivirus software. I strongly recommend Comodo Internet Security (free AV and firewall) Do a scan.
Get the latest version of CCleaner and run it a few times
Scan with Spybot or whatever anti-malware package you want.
Defrag the hard drive. Check out Defraggler.
With CCleaner you can get rid of most of the programs that start with windows. And you can uninstall all those unnecessary apps. And you can clean up the registry.
OK that's for starters 